Teiko- Publications

Application of sample stabilization and mass cytometry in global oncology trials: lessons from regulatory T cell monitoring

Michael Lahn, Giusy Di Conza, Kristina Magee, MD, PhD, Sacha Martiny, Carly Lancaster, PhD, Li-Chun Cheng, PhD, Ramji Srinivasan

AI-Assisted Cytometry Panel Design for Cancer Immunotherapy

Landon Wellendorf, Ramji Srinivasan, Carly Lancaster PhD, Hannah Selken, Sacha Martiny, Kristina Magee MD PhD, Justin Jarrell PhD, Li-Chun Cheng PhD | teiko-labs.com/design | SITC 2026

Antigen density quantification by mass cytometry using quantum simply cellular bead-based calibration

Diego López Ph.D., Carly Lancaster Ph.D., McKenna Coughlin, Sacha Martiny, Landon Wellendorf M.Eng., Kristina Magee MD, Ph.D., Hannah Selken, Justin Jarrell Ph.D., Ramji Srinivasan, Li-Chun Cheng Ph.D.

Point-of-collection whole blood fixation enables robust phosphoprotein profiling by mass cytometry for longitudinal clinical trials

Lily Shang, PhD; McKenna Coughlin; Kristina Magee, MD, PhD; Carly Lancaster, PhD; Sacha Martiny; Landon Wellendorf; Justin Jarrell, PhD; Ramji Srinivasan; Li-Chun Cheng, PhD

Enhanced Preservation of Real-World Diseased Immune Signatures in Stabilized Whole Blood Enables Longitudinal Studies of Multiparameter Immune Monitoring

Chaoyuan Kuang, MD, PhD, Sacha Martiny*, Angelynn Huang*, McKenna Coughlin, Landon Wellendorf, Justin Jarrell, PhD, Ramji Srinivasan, Li-Chun Cheng, PhD

Long-Term Whole Blood Stabilization Preserves Immune Phenotypes for Multiparameter Cytometry

Carly Lancaster, PhD, Sacha Martiny, Kristina Magee, MD, PhD, Landon Wellendorf, MEng, Hannah Selken, Justin Jarrell, PhD, Ramji Srinivasan, Li-Chun Cheng, PhD

Pre-Analytic Stabilization of Bone Marrow Aspirates for Acute Myeloid Leukemia Measurable Residual Disease Testing by Spectral Flow Cytometry

Lily Shang, Aaron Logan, Emma Searle, Karen Rees-Unwin, Thanuja Gali Ramamoorthy, Olaf Zoellner, Diego Lopez, Carly Lancaster, Sacha Martiny, Arya Iyer, Sergey Ingram, Landon Wellendorf, Justin A. Jarrell, Ramji Srinivasan, Li-Chun Cheng

Programmable Panels: A Web-Based Design Studio to Accelerate Custom Cytometry Panel Development for Clinical Immune Profiling

Carly Lancaster PhD, Landon Wellendorf, Hannah Selken, Kristina Magee MD PhD, Justin Jarrell PhD, Ramji Srinivasan, Li-Chun Cheng PhD

Unsupervised clustering identifies a CD161⁺ MAIT-like T cell population associated with anti–PD-1 response and immune-related toxicity in stage II-IV melanoma

Selken et. al (AAI 2026)

Teiko-powered spectral flow reveals dose-dependent immune dynamics in Obsidian's TIL trial

Amaria et. al SITC Spring (2026)

T cell phenotypes, differentiation states, and functional markers remain stable for two years using a blood collection kit for longitudinal, high parameter cytometry

Coughlin et. at SITC (2026)

Evaluation of CC blood collection tubes as a stabilization method for pharmacodynamic flow cytometry in multi-site clinical trials

Lancaster et al. SITC (2025)

It’s on-site: Eliminating site-to-site variability with whole blood collection kits using 30+ marker TokuProfile mass cytometry assay

Sigal & Cheng et al. SITC (2024)

Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4+ naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma

Kovacsovics-Bankowski & Sweere. JITC (2024)

Mass cytometry immune profiling to detect signatures of clinical activity of bintrafusp alfa in patients with advanced non-small cell lung cancer

McAdams & Medina et al. ASCO (2023)

Peripheral immune features associated with severe adverse events in melanoma

Healy & Kovacsovics-Bankowski et al. SITC (2022)

Immune features associated with clinical benefit and adverse events in response to immunotherapy in UC patients

Healy & Sweere et al. Cancer Res (2023)

Peripheral immune features associated with severe immune-related adverse events and clinical benefit in checkpoint inhibitor-treated melanoma

Kovacsovics-Bankowski & Sweere. SMR (2023)

Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients

Burnett, Okholm, & Tenvooren, et al. Immunity (2022)

Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response

Levine & Hiam-Galvez et al. Immunity. (2021)

Comprehensive immune monitoring of clinical trials to advance human immunotherapy

Hartmann et al. Cell Rep (2019)

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

Rahim, Okholm, & Jones et al. Cell (2023)

Systemic immunity Is required for effective cancer immunotherapy

Spitzer, Carmi, & Reticker-Flynn et al. Cell (2017)

Publications by Teiko and friends.

Read original work on cytometry methods, specimen collection, and biomarker discovery and validation.

Application of sample stabilization and mass cytometry in global oncology trials: lessons from regulatory T cell monitoring

AI-Assisted Cytometry Panel Design for Cancer Immunotherapy

Antigen density quantification by mass cytometry using quantum simply cellular bead-based calibration

Point-of-collection whole blood fixation enables robust phosphoprotein profiling by mass cytometry for longitudinal clinical trials

Enhanced Preservation of Real-World Diseased Immune Signatures in Stabilized Whole Blood Enables Longitudinal Studies of Multiparameter Immune Monitoring

Long-Term Whole Blood Stabilization Preserves Immune Phenotypes for Multiparameter Cytometry

Pre-Analytic Stabilization of Bone Marrow Aspirates for Acute Myeloid Leukemia Measurable Residual Disease Testing by Spectral Flow Cytometry

Programmable Panels: A Web-Based Design Studio to Accelerate Custom Cytometry Panel Development for Clinical Immune Profiling

Unsupervised clustering identifies a CD161⁺ MAIT-like T cell population associated with anti–PD-1 response and immune-related toxicity in stage II-IV melanoma

Teiko-powered spectral flow reveals dose-dependent immune dynamics in Obsidian's TIL trial

T cell phenotypes, differentiation states, and functional markers remain stable for two years using a blood collection kit for longitudinal, high parameter cytometry

Evaluation of CC blood collection tubes as a stabilization method for pharmacodynamic flow cytometry in multi-site clinical trials

Comparison of Whole Blood Preservation Methods for Cytometric Analysis

Unsupervised clustering reveals cell population in melanoma patients treated with anti-PD-1 therapy

Comparison of Whole Blood Preservation Methods for Cytometric Analysis

25-Marker Spectral Flow Panel for Immune Profiling in Fixed Whole Blood

Unsupervised clustering reveals cell types in 40 specimen aGVHD PBMC cytometry dataset

Is Fresh Really That Fresh? Time-Dependent Quality Loss in Live Specimens.

Unsupervised clustering reveals cell types in 145 specimen melanoma PBMC cytometry dataset