Immune features associated with clinical benefit and adverse events in response to immunotherapy in UC patients

Healy & Sweere et al. Cancer Res (2023)

Poster Highlights

  • To identify cell signatures associated with response and irAE development, we used mass cytometry to characterize the immune system in patients with urothelial cancer receiving aPD-1 therapy.
  • We found several immune features associated with survival, response to immunotherapy and presentation of adverse events
  • While some immune features were only associated with response, others were also associated with irAE.
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