TokuFocus: Announcing “focused” panels for spectral flow and mass cytometry

TokuFocus: Announcing “focused” panels for spectral flow and mass cytometry.

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Teiko’s cytometry services allow you to measure 146 - 840 of populations, a 6-17X increase compared to conventional 13-marker flow cytometry panels.

However, many immunotherapy developers are worried about the cost and need of measuring the extra populations. Drug developers sometimes say, “I just need to measure TBNK by flow first. If the drug shows activity in the TBNK populations, then, and only then, would I care about the other populations.”

The TokuFocus is designed with this drug developer in mind. You can start with a TBNK panel subset, covering 10 markers at $1,000 per specimen. You can then upgrade to the full panel at any time within a year for an additional $900 per specimen. In short, you get the option to see the rest of the immune tree when you want (and only when you want).

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What problem TokuFocus solves:

• Drug developers who need a quick analysis of TBNK populations but who don’t want to lose the option of detailed immune population analysis. These developers want to focus on TBNK populations first and analyze the rest of the immune tree after achieving successful readings.

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How it works:

• Each sample will be run on a full, 25-marker or 41-marker panel.
• For $1,000 per specimen, customers can access the data for a basic 10-marker TBNK panel. 
• With the software-based upgrade, customers can unlock access to the data for the full panel for $900 per specimen, without having to run additional samples. 
• Required minimum specimens by cohort
  • Mass Cytometry: 20 specimen
  • Spectral Flow Cytometry: 50 specimen

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What do I get after I upgrade?

• Gated Data
• FCS and GatingML Files
• Dashboard: Immune Cell Composition, Box and Time Series Plots
• 2 Consulting Hours

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Key Features: 

With the 10-marker panel, customers can access features included in our core analysis tier. This includes data tables, sample and gating QC, and manually gated statistical analysis. Raw data files, like FCS and GatingML are only available after unlocking the remaining channels. These features will be available on Teiko’s dashboard, at app.teiko.bio. 

Within a year, customers can upgrade to unlock the data for the full panel. After upgrading, the analyzed data will be available within the dashboard, assuming a 50 specimen order.

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FAQ:

Can I do this on a custom panel? ‍

Not yet (something in the works for the future)! This is built for our off-the-shelf panel.

Can I pick the subset‍

Something we're thinking about, but not with this release. Here are the markers included in our basic TBNK panels:

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What if I want to run multiple cohorts?‍

We can support this, however spectral flow requires 50 specimens per cohort, and mass cytometry requires 20 specimens per cohort.

Is the full gating tree available?‍

Yes, you will get the full gating tree on the dashboard. You’ll see the unavailable populations greyed out.

Can I cherry pick which samples to upgrade? That is, if I send you 50 samples, can I upgrade 30?

Not yet, you cannot select which samples to upgrade. That is, the upgrades are “all or nothing.”

How do you do unsupervised analysis?

We don’t do unsupervised analysis on the focused panel. If you’re interested in that, you have to unlock the remainder of the panel. Once you unlock the panel, you have the option to upgrade for an additional fee.

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Stop second-guessing. Start with focus.

‍TokuFocus is live - begin with TBNK today!

Get the insights you need now, with the option to go deeper when you're ready.

Message us here to get started. For pricing, quotes, or more information, visit www.teiko.bio or message us at teiko.bio/contact.